Are we talking about Requiem? Because fuck vampires, those Draugr are fucking worse. Jesus. The first dungeon where you need to get the stone slab for that mage was nearly impossible at level 5. My weapons simply did not do any damage to those bastards.
What did you use?
Because draugr, while though, aren't invincible and they have sort of zombie-like tactics (they don't care about taking damage).
Did you use bow? Draugr are immune to normal arrows. You need enchantments (optimally fire or turn undead) or silver arrows to damage them with a bow. They don't have any functioning organs or blood vessels to be damaged by arrows, so shooting them merely turns them from walking, dessicated lumps of dead meat walking into irate, walking, dessicated lumps of dead meat with lots of arrows sticking out.
Bludgeons are also somewhat ineffective, because they don't suffer from internal bleeding while their flesh still cushions their bones (standard skeletons just shatter when bludgeoned, OTOH).
Silver weapons in general help.
Vampires OTOH rape you with perked up ice spikes at distance and sucking your health close up, while also resisting arrows.
Unless you can arrange massive instant fire damage, anti-undead effects, humongous physical damage or some sunlight, you're fucked.
I had to lure them through traps to kill them and even then, I couldn't finish the dungeon because there's almost no way around the Draugr Lord fight.
This is a good thing, btw.
Odd, I've only met one rape incarnate that was so tough the blade trap failed to kill him in first two swings, the rest, while not easy, was fair.