OlSheep:
A lot better than your first one. I don't think it fits the game at all well thematically though. It also feels rather actiony, and could do with polishing up. It's nice that it's somewhat darker than others - so not so in-your-face. However, I think mantra_n's is better in this regard, while Elhoim's and Androids are better thematically.
Yours kind of captures the worst of both worlds
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Having said all that, I think I'd be fine playing a game with that interface (aesthetics of interfaces doesn't really bother me as a player). I wouldn't be thinking "wow - what an interface", but neither would I think "who designed this crap!?".
A great improvement, but don't quit the day job just yet
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Elhoim:
I like the latest version a lot. The clarity is much better, and I prefer the frame. The only thing that bothers me about it now is that the weapon slots stand out like buttons, rather than depress like... depressions. Perhaps having them a different color would work too, but I do think that switching the shadows to have them depressed would help a little.
Also in general terms, is the "save" icon necessary? Wouldn't it work just to have the player hit Escape? I just don't think having a "save" icon on the interface helps with TEH IMERSHUN. Since it's not necessary (everyone will expect Esc to work - and you could provide a save hotkey), and a disk hardly fits the post-apoc-romelike feel, why not lose it?