I have to say that all this whining about difficulty makes my mouth water. I wish I had the time to try it out myself, and see if I have what it takes to beat the game.
If you never have to reload, then it's not worth your time.
I enjoy high difficulties too, but the fact of the matter is that (at least early on) PF:K does it rather poorly. It's not really "difficulty", just massive "swingyness", leading to reloads until RNGesus favors you, combined with poor feedback from the game as to what is going on and why. For example, right at the beginning, even the minor buffs enemies get on, say, Hard, makes a huge difference, and a single hit or miss can kill either you or the enemy, resulting in a game of randomized rocket-tag.
there's the spider-swarms, in your first "real" subquest. In the quest, there are spider-swarms, and you can try to hit them all day without success. This is because spider-swarms can only be hit by AoE effects, but the game never tells you this at all, nor equip you with the necessary items to use (because no-one you've met up until that point has any means of AoE damage, so unless you're a Wizard, Alchemist or Sorcerer, you're basically SOL). And how many Flasks of Alchemist's Fire or Acid do you need? Well *I* needed 10ish, which is a crazy assumption that the player would have at that point.