V
Unlike Dante and Nero, V has very little demonic power and seemingly a normal human, instead his abilities comes from his pact with his three demons and is capable of casting a huge variety of magic spells. One spell seems to involves creating many duplicates of his cane to attack many enemies at once.
Familiars
V has the ability to summon demons to fight on his behalf. When not call upon, the demons are embodied as tattoos on V's body and in his hair, turning it from white to black. When they are summon, the corresponding tattoo to each demon will disappear and his hair turns back to its original color.
Shadow: This demon familiar usually takes the form of a quadruped beast, only to shape-shift into blades, needles, and all manner of nasty weapons to act as vanguard. Through Shadow, V can also move at faster speeds than normal. V can also ride on Shadow as a form of transportation.
Griffon: This avian monstrosity can always be found somewhere around V, usually flapping its beak with some inappropriate jab. Griffon brings the thunder with electrified long-range attacks, or can give V a lift if close by. Griffon is the only one that knows human language and acts as the interpreter for Shadow and Nightmare so others can understand them.
Nightmare: V can unleash his full power to call upon this gargantuan demon. When summoned, Nightmare may crash onto the battlefield like a meteorite, or burst through parts of the environment to heed the call. Its sluggish movements belie unsurpassed strength and nigh-invulnerability. Wherever Nightmare appears, its massive fists or brutal laser beams are the last thing enemies ever see.
Gameplay
In terms of combat, V uses his cane and book with the letter "V" on it as weapons. He's also capable of summoning different types of demons that will aid him in the battle and casting a huge variation of spells. Due to his unique gameplay style, V described to be a "tricky" and strategic character to use in battle. When playing as V, maintaining a distance is key while his familiars are fighting and as long V doesn't take damage, the battle can continue. When quickly evading or attempting to ride on Shadow or fly with Griffon, V must have his familiars close to him or call them back to his position.
V's demons can be strengthen and learn new abilities over the course of the game. However, V's familiars cannot kill other demons and V must land the finishing blow. When enemies are close to death, they will start to stagger and turn violet, signalling for V to finished them off with his cane.
The demons are manually directed by V, but Griffon and Shadow can fight automatically, but having them fight automatically will use up V's D.T gauge. With Nightmare, summoning him consumes the D.T. gauge and it also decreases when Nightmare attacks. Due to Nightmare's slow movement, Nightmare essentially cannot transverse the ground very well and isn't ideal to use when surrounded by enemies. Nightmare also fights automatically, but can be directly controlled by V when he climbs on his shoulder and pierced him with his cane. As along Nightmare is controlled by V, V can kill enemies off using Nightmare.
The familiars can take damage and will revert to their core state after taking too much. In their core state, they cannot attack and cannot be summon again for a certain amount of time. If Griffon and Shadow are in their core state, summoning Nightmare is a quick way to revive them. Another way to quickly revive the familiars from their core states is for V to stand close to them, the closer V is the faster the familiars can revive.
In order to fill V's D.T. gauge, V has to read his book and the closer V is to his opponents while reading, the faster the gauge will fill.
Itsuno stated in a Famitsu interview that V caused the most trouble when developing Devil May Cry 5. At the New York Comic-Con 2018, he also stated that V was actually his favorite character.