Green Ronin dit it first for 3e. At least, only during the Old Testament era.
Sweet, do they stat Moses? Can you kill him and take his robes? What sorts of bonuses do you get from looting the Ten Commandments?
Yes, he has 3 levels in Paladin. Moses' robes don't do anything special, but the Mantle of Elijah grants 5 levels in the Levite Priest class, increasing the wearer's level if they already are.
The Tablets of the Law radiate Magic Circle Against Evil continuously, and within its range it grants a +4 bonus against mind-affecting spells, and all Evil or demon-possessed creatures have to make a DC26 Will save every turn or be struck blind. 60 lbs. total.
Now the issue is that they're in the Ark of the Covenant. Touching it without being a Levite priest who ritually pure forces a DC30 Piety skillcheck or be struck dead by divine lightning. Passing it deals 10d6 damage + 1 for every negative Piety that you have. Trying to destroy the Ark will cause the cherubim on top to come to live, which are CR22 monsters which for starters are immune to antimagic and can throw divine lightning bolts that are DC30 Reflex save or die, 15d6 on save. By strict RAW it also radiates a Magic Circle against Evil, even without the Tablets inside. The Ark also contains the Golden Pot of Mana (creates manna for 60 people at a time, does not refill on Sabbath or on holy days) and the Rod of Aaron, which knows Bestow Affliction, Control Weather, Create Water, Creeping Doom, Plant Growth (on the Rod itself), Polymorph Any Object (itself into a snake), Prayer and Curse Water (except it produces blood, not unholy water). Total weight including artifacts is 440 lbs.
They also added stats for Ramses II (level 20 Paladin/Aristocrat/Master Charioteer multiclass with prestige class) and Cleopatra (21 Charisma, has an automatic increase of two levels around men and Charisma checks can improve it even further).